Journal of Chromatography & Separation Techniques

Journal of Chromatography & Separation Techniques
Open Access

ISSN: 2157-7064

Research Article - (2015) Volume 6, Issue 3

A Simple Protein Precipitation-based Simultaneous Quantification of Lovastatin and Its Active Metabolite Lovastatin Acid in Human Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry using Polarity Switching

Wujian J1, Kuan-wei P1, Sihyung Y1, Huijing S2, Mario S2 and Wang MZ1*
1Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA
2Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
*Corresponding Author: Wang MZ, Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Ave, Lawrence, KS 66047, USA, Tel: 785-864-1899, Fax: 785-864-5736 Email:

Abstract