Transcriptomics: Open Access
Open Access

Megha Wal

Biography

Dr. Megha Wal obtained  Ph.D. in the lab of Dr. B. Franklin Pugh at The Pennsylvania State University, University Park, where she conducted genome-wide studies to investigate the mechanisms governing nucleosome organization in the budding yeast Saccharomyces cerevisiae. It is well known that the eukaryotic genome is packaged into highly compacted nucleosomal arrays called chromatin. Each nucleosome contains 146-bp DNA, which is tightly wrapped around a histone octamer core. Factors such as DNA sequence, chromatin remodelers (a class of enzymes) and transcription influence nucleosome locations that affects every cellular process that requires access to DNA. Thus, the rules determining nucleosome locations are crucial to understand. 

Research Interest

Biochemistry, Genomics, Microbiology, Molecular Biology, Genetics and Cell Biology. Specifically, my expertise is in epigenetics, epigenomics, chromatin biology, transcription biology and gene regulation