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Associate Research Professor, Indiana Center for Vascular Biology and Medicine
Matthias Clauss received his Ph.D. 1988 from the Ruprecht-Karls-University, Heidelberg, Germany. He his Postdoctoral Fellowship with Dr. David Stern, Columbia University, New York City, where he discovered novel endothelial cell activating proteins such as EMAP II. His interest in angiogenesis made Dr. Clauss join Dr. Werner Risau 1992 at the Max-Planck-Institute in Germany, where he addressed the role of inflammation in blood vessel grow and repair. Since 2003 Dr. Clauss is a member of the Indiana Center for Vascular Biology and Medicine and Associate Research Professor for Cellular & Integrative Physiology and Microbiology & Immunology. He has published over 60 peer reviewed research articles and his editor of the book “Mechanisms of angiogenesis”.
Matthias Clauss studies the balance of angiogenesis in repair with focus on the pro-angiogenic vascular endothelial growth factor (VEGF) and the anti-angiogenic endothelial monocyte-activating polypeptide II (EMAP II), their receptors and cell signaling. He also studies the role of adult stem cells in tissue repair and how inflammation can cause cellular senescence of these cells. Furthermore, Dr. Clauss and his team analyze mechanisms leading to cardiovascular complications in the HIV positive population with focus on the intracellular HIV-Nef protein.