Jichi Medical University, Japan
Dr. Masafumi Takahashi is a Professor of Division of Bioimaging Sciences, Center for Molecular Medicine, Jichi Medical University, Japan. He was Associate Professor, Department of Cardiovascular Medicine, Shinshu University Graduate School of Medicine, Japan. 2001–2003 He served as Assistant Professor, Division of Organ Replacement Research, Center for Molecular Medicine, Jichi Medical University, Japan.1999–2001 Instructor, Department of Cardiovascular Medicine, Jichi Medical University, Japan 1997–1999 Chief Physician, Miyagi Hanayama Village Public Clinic, Japan 1995–1997 Senior Fellow, Department of Cardiology, University of Washington, Seattle, USA (Professor Bradford C. Berk) 1991–1993 Senior resident in Cardiology, Miyagi Prefectural Semine Hospital, Japan 1989–1991 Junior resident in Internal Medicine, National Sendai Hospital, Japan. 1993–1997 Ph.D., Jichi Medical University 1983–1989 M.D., Jichi Medical University.
The research interests of Dr. Takahashi are the molecular mechanisms and the development of novel effective therapies for atherosclerosis and ischemic heart diseases, especially in the role of inflammation and regeneration. In particular, Dr. Takahashi focuses on the inflammasome, a large multiprotein complex which plays an important role in autoinflammatory responses by participating in the production of IL-1beta, as well as SDF-1/CXCR4 system, a chemokine and its receptor system involved in the processes of chemotaxis, cell proliferation and survival, angiogenesis and tissue regeneration.