Dr. Nora Calcaterra
The University of Nevada, Reno, USA
Dr. Calcaterra’s lab develops two research lines trying to answer questions related to the development of craniofacial structures. The approach is at two levels: the modelling of human craniofacial disorders (cleft palate, aberrations in the formation of maxilla and mandible, etc.) employing the zebrafish as experimental model, and the characterization of molecular mechanisms that control gene expression by involving single-stranded nucleic acid binding proteins. Dr. Calcaterra’s is funded by NIH.
Dr. Calcaterra’s research interests includes laboratory technologies of gain- and loss-of-function of specific proteins (loss of function by microinjection of morpholinos or dominant negative protein overexpression and gain of function by overexpression of wild protein), generation of transgenic fish lines, as well various techniques of developmental biology. In addition, molecular biology techniques, biochemistry and spectroscopy (absorption, fluorescence, and circular dichroism) approaches are usually employed.