Dr. Charles E Egwuagu
Chief of Molecular Immunology Section, Laboratory of Immunology
National Eye Institute, USA
Dr. Charles E. Egwuagu is an Epidemiologist/Immunologist and Chief of the Molecular Immunology Section, National Eye Institute, NIH. After receiving his Ph.D, MPH and M.Phil from Yale University, Dr Egwuagu served as a Commissioned Officer of the USA Public Health Service for ten years, attaining the rank of Captain (06).
Dr. Charles E. Egwuagu major research focus is on the genetic modification of eukaryotic cells and engineering of genetically altered mouse and rat strains. These novel cell lines or rodent strains allow us to investigate molecular and cellular mechanisms that regulate development of CNS inflammatory diseases, such as uveitis, multiple sclerosis and age-related macular degeneration (AMD). Particular interest is on cytokine signaling and epigenetic mechanisms that regulate lymphocyte development and cell-fate decisions. Our goal is to develop cytokine-based therapy for autoimmune and neurodegenerative diseases.