ISSN: 2168-9296
Department of Nutrition Sciences, Larestan University of Medical Sciences, Larestan, Iran
Research Article
Narrative Review: Therapeutic Approach of Sulphorafane for Breast Cancer
Author(s): Zeinab Salim**
Objective: To comprehensively review the current evidence on the mechanisms of action, efficacy, delivery approaches and combination therapy prospects of sulforaphane for breast cancer management. Background: Breast Cancer (BC) is a leading cause of cancer mortality worldwide. It needs improved prevention and treatment strategies because of the metastasis and drug resistant problems. Sulforaphane is a natural compound derived from cruciferous vegetables that has shown potent anticancer activity.
Methods: This narrative review was done by a systematic search across PubMed, Google Scholar, Scopus and Clinical Trials Government (CTG) from 2004 to 2023. Included articles were 31.
Results: Numerous studies demonstrated sulforaphane's antiproliferative and pro-apoptotic effects against breast cancer cells and cancer .. View More»