ISSN: 2471-9315
Department of Pharmacology, Gomal University, Dera Ismail Khan, Pakistan
Research Article
Evaluation of In Silico and In Vitro Inflammatory and Biofilm
Targets Inhibition by the Polyphenols of Prunus persica L. Spp; Functional Food Based Approach for the Illnesses Associated with Inflammatory and
Microbial
Author(s): Abdul Rafey*, Tooba Khalid, Madiha Ahmad, Fakhar ul Mahmood, Farhat Shaheen, Abdul Haleem Shah and Samir Anis Ross
Aims and objectives: Considering the increasing resistance of bacteria to antibiotics and the presence of antibacterial
agents in plants being served as functional food choice for many ailments. Chronic diseases become the leading
cause of more than 50% of deaths around the world. The real reason is inflammation linked to the microbial
association as biofilm trend behind all chronic diseases like congestive heart failure, cognitive disorders, diabetes and
associated comorbidities, hypertension. Bioactive compounds in functional foods are responsible for all these health
benefits present in them. Research has suggested that fruits of Prunus persica L. rich in polyphenolic constituents as
major bioactive compounds that possess remarkable antibacterial properties. The aim of this study was to evaluate
the anti-biofilm and anti-inflammatory p.. View More»
DOI:
10.35284/2471-9315.22.8.228