Journal of Clinical Trials
Open Access

Shandong University of Traditional Chinese Medicine, Jinan, 250355, China

Publications

• Research Article   
  Therapeutic Targets and Mechanism of Banxia Xiexin Decoction on Precancerous Lesions of Gastric Cancer: Network Pharmacology
  Author(s): Guoxiu Zu, Keyun Sun, Ling Li, Xiuli Zu, Tao Han and Hailiang Huang*
  
  Background: Precancerous Lesions of Gastric Cancer (PLGC) is a common gastrointestinal tract and digestive system disease that lacks effective therapeutic drugs with good curative effects and few adverse reactions. Traditional Chinese medicine (TCM) has the advantages of multiple components, multiple channels, and fewer adverse reactions in the treatment of PLGC. Although Banxia Xiexin Decoction (BXD) demonstrates a good therapeutic effect on PLGC, the pharmacological mechanism underlying its anticancer effect is still unclear. Methods: We used a network pharmacology strategy, including the construction and analysis of a complex drug-disease network, to explore the complex mechanism of BXD treatment of PLGC. In addition, molecular docking technology was used to preliminarily study the binding ability of the potential active c.. View More»
  DOI: 10.35248/2167-0870.21.s12.003

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