Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

Tanay Chakrovarty

Department of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh

  • Review Article   
    The Emerging Strains of SARS-CoV-2 and Current Vaccine Strategies: A Systemic Review
    Author(s): Tanay Chakrovarty, Ali Ahsan Setu, Sourav Dutta Dip, Md. Shazid Hasan and Md. Tanvir Islam*

    The ongoing ravaging pandemic caused by SARS-CoV-2 continues to emerge by acquiring new mutations. Several recent mutations under different clades render the virus to bind more efficiently to the human ACE-2 (Angiotensin Converting Enzyme-2) with its spike protein. Detection inefficiency due to mutation in the spike protein (deletion of Δ69-Δ70 amino acid residues) misleads the flawless result of the COVID-19 test is also a significant concern. Several vaccine candidates have been designed to diminish this pandemic, from which four have been authorized due to exigency and more candidates are in the pipeline. The prime revealing mutations from different lineages (lineage B.1.177, B.1.1.7, B.1.351, and B.1.1.28 by PANGOLIN) has up risen several questions, including the vaccine efficacy against the mutated strains, alternate detection methods, evading pot.. View More»
    DOI: 10.35248/1948-5964.21.s20.001

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