Journal of Clinical Trials

Journal of Clinical Trials
Open Access

ISSN: 2167-0870

+44 1478 350008

Sen Yang

Department of General Practice, Yangpu Hospital, Tongji University School of Medicine, Shanghai, China

  • Research Article   
    Risk Factors and a Prognostic Scoring System for Severe Disease in Patients with COVID-19: A Retrospective Cohort Study
    Author(s): Sen Yang, Le Ma, Yu-Lan Wang, Qiang Tong, De-Hua Yu, Sheng-Ming Dai and Ran Cui*

    Background: The corona virus disease 2019 (COVID-19) has made a big threat on the global public health. The aim of the study is to comprehensively explore the risk factor for severe disease events (intensive care, invasive ventilation, or death) in patients with COVID-19, and to establish a prognostic scoring system. Methods: Patients with laboratory-confirmed COVID-19 admitted to the Wuhan Leishenshan Hospital from February 13 to March 14, 2020, was retrospectively analyzed. Demographic data, symptoms, laboratory values at baseline, comorbidities, treatments and clinical outcomes were extracted. The LASSO and multivariate logistic regression models were developed to explore the risk factors for critical-ill events. A risk model was established via nomogram. Results: 463 COVID-19 patients were in.. View More»
    DOI: 10.35248/2167-0870.21.11.470

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