Journal of Leukemia
Open Access
ISSN: 2329-6917
ISSN: 2329-6917
Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, King Fahad Specialist Hos, Saudi Arabia
Research Article
The Clinical Outcomes of Pediatric T-Cell Leukemia ,A Retrospective Analysis, a Single Centre Experience
Author(s): Safa Mohammed, Hala Omer, Maher ELdoussouki, Ashraf Khairy, Fatimah Adel Alnaim and Mohammed Saleh Almajed, Saad Aldaama*
Introduction: T-cell Acute Lymphoblastic Leukemia (T-ALL) is a rare and aggressive malignancy, accounting for 12-15% of pediatric ALL cases. Despite advancements in treatment, relapse rates remain high (~20%). Prognosis depends on factors such as genetic mutations, Minimal Residual Disease (MRD) status, and response to therapy.
Objectives primary objective: To evaluate the clinical outcome of pediatric patients (0-15 years) diagnosed with T-cell Acute Lymphoblastic Leukemia (T-ALL) treated at King Fahad Specialist Hospital -Dammam between January 2012 and December 2022.
Secondary objectives: To identify prognostic factors that may influence treatment outcomes in pediatric T-ALL. To assess the impact of different treatment strategies and survival and relapse rates. To explore associations between clinical characteri.. View More»