Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Department of Dermatology, Instituto Boggio, Sao Paulo, Brazil
Research Article
Rejuvenation of Frontal and Periorbital with Hyaluronan Hybrid Cooperative Complex (HCC): A Novel Technique
Author(s): Juliana Schinzari Palo*, Gladstone Eustaquio de Lima Faria, Maria Clara Lopes Nobre, Ana Carolina Henriques Ribeiro Machado and Ricardo Frota Boggio
Background: Hybrid Cooperative Complex (HCC) is a novel molecule, launched worldwide in 2016, which contains
ultrapure high and low molecular weight hyaluronic acid stabilized in a thermal process and without chemical
additives, and it is indicated for tissue remodeling and improvement of sagging skin. It is proved that HCC can
stimulate the production of elastin and collagen by keratinocytes and fibroblasts, differentiation of steam cells into
adipocytes, and accelerate the wound healing process. It is currently described for treating the mid and lower third of
the face, but not the upper third. Its great integration capacity and uniform diffusion are favorable characteristics for
the forehead and periorbital region, with tissues frequently adhered to the underlying musculature.
Objective: To evaluate the effectiveness and s.. View More»
DOI:
10.35841/2329-9509.23.14.653