Journal of Clinical Trials
Open Access

Department of Critical Care Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Publications

• Research Article   
  Early Sequential Risk Stratification Assessment to Optimize Fluid Dosing, CRRT Initiation and Discontinuation in Critically Ill Children with Acute Kidney Injury: Taking Focus 2 Process Article
  Author(s): Jean-Philippe Roy*, Kelli A. Krallman, Rajit K. Basu, Ranjit S. Chima, Lin Fei, Sarah Wilder, Alexandra Schmerge, Bradley Gerhardt, Kaylee Fox, Cassie Kirby and Stuart L. Goldstein
  
  Background: Acute Kidney Injury (AKI) is common in critically ill children and is associated with increased morbidity and mortality. Recognition and management of AKI is often delayed, predisposing patients to risk of clinically significant fluid accumulation (Fluid Overload (FO)). Early recognition and intervention in high risk patients could decrease fluid associated morbidity. We aim to assess an AKI Clinical Decision Algorithm (CDA) using a sequential risk stratification strategy integrating the Renal Angina Index (RAI), urine Neutrophil Gelatinase-Associated Lipocalin (NGAL) and the Furosemide Stress Test (FST) to optimize AKI and FO prediction and management in critically ill children. Methods/Design: This single center prospective observational cohort study evaluates the AKI CDA in a Pediatric Intensive Care Unit (PICU). Every patient.. View More»
  DOI: 10.35248/2167-0870.20.10.435

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