Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Department of Biochemistry, Drs. Tribedi & Roy Diagnostic Laboratory, Kolkata, India

Publications

• Research Article   
  Variability In Directly Measured Ldl-Cholesterol In Dyslipidaemic Specimens: Is There A Cause For Concern ?
  Author(s): Rajarshi Sarkar*
  
  Background: Reporting directly measured homogeneous Direct Low-Density Lipoprotein Cholesterol (D-LDL) becomes imperative especially in tertiary level laboratories which have to frequently deal with dyslipidaemic specimens. In absence of credible studies involving dyslipidaemic specimens on comparability of test results between different platforms or between different platforms and reference methods, reporting of D-LDL becomes very uncertain. Methods: The current study includes 328 subjects classified from Type I to Type V according to Fredrickson classification of dyslipidaemia. Standard lipid profile including D-LDL was tested on their serum specimens and D-LDL was repeat tested after saline dilution on three platforms viz AU5800, Alinity ci and Cobas Pure. Calculated LDL-Cholesterol for all the specimens were derived from the NIH.. View More»
  DOI: 10.35248/2736-6588.23.6.275

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