Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Integrative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200 Kepala Batas, Penang, Malaysia
Research Article
Antioxidant, Antiproliferative Activities and Chemical Profile of Clinacanthus nutans Leaf Extracts Processed Using Two Different Pre-Extraction Drying Methods
Author(s): Zaleha Md Toha, Nor Hasyimah Haron, Nik Nur Syazni Nik Mohamed Kamal and Hasni Arsad*
Introduction: Clinacanthus nutans (CN) is a medicinal herb that is traditionally used in Southeast Asia as a treatment
for disease and prevention of cancer.
Objective: The goal of this study was to investigate the effects of different drying processes on properties of CN.
Methods: Air dried (ADDCM) and oven dried (ODDCM) leaves were extracted using the dichloromethane (DCM)
Soxhlet extraction method. Antioxidant activity of the extracts was measured using the 2, 2-diphenyl-1-picrylhydrazyl
(DPPH) scavenging assay. The chemical profile of the extracts was determined using gas chromatography-mass
spectrometry (GC-MS) analysis, and the antiproliferative activity was tested using MCF-7 (breast cancer) and MCF-
10A (normal breast) cell lines and the Sulphoromide B assay.
Results:.. View More»
DOI:
10.35248/2167-0412.20.9.361