Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

Nada Sherif

Department of Biochemistry, Faculty of Pharmacy, German University, Cairo, Egypt

  • Research Article   
    HIV Immune Complex as a New Promising Vaccine Eliciting Broad Immune Response, Alternative to Conventional Vaccine
    Author(s): Sherif Salah Hesen*, Ghaleb HA and Nada Sherif

    Aim: Based on this hypothesis a new biological combination termed V20E immune peptides comprising HIV viral antigen and a non-specific HIV antibodies has been formulated in oral and injectable form for inhibiting or preventing the HIV infection. Introduction: A new assumption assumes that CD4+ T-cell can induce the production of a pathogenic broadly neutralizing anti-HIV antibodies to mask a proportion of corresponding HIV antigens in immune-complex form (Ag/ nAbs) antigen/neutralizing antibody for a long time preventing its attacks by CD8+ cytotoxic T-cells and anti-viral drugs. Materials and Methods: A pilot study was carried out on a total of twenty-five patients (21 males, 4 females; aged 28-38 years) all of them were positive for HIV antibodies and divided them into three groups I, II and.. Read More»

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