Journal of Leukemia
Open Access
ISSN: 2329-6917
ISSN: 2329-6917
Department of Genetics, University of Karachi, Karachi, Pakistan
Research Article
Management of Calreticulin Mutated Myeloproliferative Neoplasms: Real-world Outcomes from a Low-Middle Income Country
Author(s): Uzma Zaidi*, Munazza Rashid, Rifat Zubair Ahmed, Maham Fayyaz, Muhammad Nizamuddin, Nida Anwar, Gul Sufaida, Samina Naz Mukry, Munira Borhany and Tahir Sultan Shamsi
Pakistan is one of the most densely populated countries of the South-East Asian region, and rare hematological
malignancies like MPNs are not uncommon, mainly attributable to the diverse ethnicity of the population which
is endowed with discrete clinical and molecular characteristics. Being a low-middle income country, the scarcity of
health care resources cause a delay in referrals to tertiary care hospitals especially from remote areas consequently
leading to delayed diagnoses and management, resulting in dismal outcome of patients. National Institute of Blood
Diseases & Bone Marrow Transplantation is the largest tertiary care hematology center where patients from all
the four major provinces of Pakistan are referred for treatment. We prospectively studied the incidence, clinical
behavior, treatment response, and challenges in the management of patients with.. View More»
DOI:
10.35248/2329-6917.22.10.309