International Journal of Physical Medicine & Rehabilitation
Open Access
ISSN: 2329-9096
ISSN: 2329-9096
Department of Internal Medicine-B, Shamir Medical Center, Zerifin, Israel
Original Research Article
Hyperbaric Oxygen Therapy for COVID-19 Patients: A Prospective, Randomized Controlled Trial
Author(s): Amir Hadanny*, Finci Shachar, Catalogna Merav, Abu Hamed Ramzia, Korin Calanit, Levi Gabriella, Adler-Vallach Katya, Tarasula Natalya, Mahagna Hamad, Wang Zemer, Lang Erez, Zemel Yonatan, Bechor Yair, Rahimi-Levene Naomi, Shapira Yonatan, Gorelik Oleg, Tzur Irma, Ilgiyaev Eduard, Mizrachi Avi, Shiloach Eli, Maor Yasmin, Levtzion-Korach Osnat and Efrati Shai
Rationale: The hallmarks of pulmonary derangement due to severe COVID-19 disease include hypoxemia and a dysregulated and excessive immune response, i.e. a "cytokine storm". Several case series reported on the beneficial effect of Hyperbaric Oxygen Therapy (HBOT) on COVID-19 patients.
Objective: The aim of the study was to evaluate the effects of HBOT on COVID-19 patients.
Design: Randomized controlled design.
Setting: Single medical center with primary level care.
Participants: Thirty-one severe COVID-19 inpatients, suffering from respiratory insufficiency (saturation lower than 94% on room air or PaO2/FiO2<300 mmHg in addition to at least one risk factor) in addition to at least one other risk factor, were randomized between May-October 2020 to HB.. View More»
DOI:
10.35248/2329-9096-22.10.624