Journal of Cancer Science and Research
Open Access

Pathology Divisions, Mochtar Riady Institute for Nanotechnology, Lippo Karawaci, Tangerang, Indonesia

Biography

Larasati YO  has been involved in many quantitative as well as qualitative studies; but her expertise are mostly related to qualitative and action research. Pathology Divisions, Mochtar Riady Institute for Nanotechnology, Lippo Karawaci, Tangerang, Indonesia

Publications

• Research Article   
  Curcuminoids Suppress the Number of Transformed-Hepatocytes and Ki67 Expression in Mice Liver Carcinogenesis Induced by Diethylnitrosamine
  Author(s): Atmodjo WL*, Larasati YO, Isbandiati D and Mathew G
  
  Background: Curcuminoids has been reported to have strong anti-oxidant and anti-inflammatory effects, however the effect of curcuminoids to hepatocytes and their proliferation in DEN (Diethylnitrosamine) induced mice liver carcinoma model is still not yet been studied in detail. Objection: To evaluate the effects of curcuminoids-containing diets in liver carcinoma mice induce with Diethylnitrosamine Methods: Forty of 5 weeks old, male Balb/C mice were administered DEN as an injection and fed with basal diet; and another group injected with DEN and fed with 0.2% curcuminoids-containing diet. Dose of injection DEN is 75 mg/kg BW/week for 3 weeks, continued with 100 mg/kg BW/week for 3 continuous weeks. Five animals in each group were sacrificed at 20 and 32 weeks after the first injection of DEN. The liver sections were st.. View More»
  DOI: 10.4172/2576-1447.1000112

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