Immunome Research
Open Access
ISSN: 1745-7580
ISSN: 1745-7580
Department of Cancer Research, Xuzhou Central Hospital, Jiangsu Province, China
Research Article
Correlation of MZT2A Expression with Immunity and Prognosis in Pan-Cancer Analysis
Author(s): Shizhang Zhan, Wenping Wang, Minghua Yan, Dan Li, Jing Liu, Xinyuan Fan, Qi Zhang, Shu-an Liu and Ruoran Li*
Purpose: Mitotic spindle tissue protein 2A (MZT2A) has the properties of the core subunit of the γ-Tubulin Ring
Complex (γ-TuRC) and is involved in mediating the formation of bipolar spindles in mitosis. The lack of MZT2A will
weaken the nucleation activity of Microtubule (MT) and slow down the rate of cell proliferation. Although there is
evidence that the expression of MZT2A plays a crucial role in the development of some tumors, there is still no
research on MZT2A in pan-cancer. Therefore, we aim to explore the prognostic value of MZT2A in a variety of cancer
types and to study its potential immune function.
Methods: This study was conducted with datasets from The Cancer Genome Atlas, the Cancer Cell Lineage
Encyclopedia, Genotype Tissue Expression and the Human Pro.. View More»
DOI:
10.35248/1745-7580.25.21.292