Professor and Head, Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center
Tel-Aviv University, Israel
Dr. Yehuda Shoenfeld is the founder and head of the Zabludowicz Center for Autoimmune Diseases, at the Sheba Medical Center which is affiliated to the Sackler Faculty of Medicine in Tel-Aviv University, in Israel. Dr. Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at the Tel-Aviv University.
His clinical and scientific works focus on autoimmune and rheumatic diseases, and he has published more than 1700 papers in journals such as New Eng J Med, Nature, Lancet, Proc Nat Acad Scie, J Clin Invest, J Immunol, Blood, FASEB, J Exp Med, Circulation, Cancer and others. His articles have had over 31,000 citations. He has written more than three hundred and fifty chapters in books, and has authored and edited 25 books, some of which became cornerstones in science and clinical practice, such as "The Mosaic of Autoimmunity", "Infections and Autoimmunity" and the textbook "Autoantibodies" and "Diagnostic criteria of autoimmune diseases", all of which were published by Elsevier and sold by the thousands. He is on the editorial board of 43 journals in the field of rheumatology and autoimmunity and is the founder and the editor of the IMAJ (Israel Medical Association Journal) the representative journal of science and medicine in the English language in Israel, and also is the founder and Editor of the "Autoimmunity Reviews" (Elsevier) (Impact factor 6.6) and Co-Editor of "Journal of Autoimmunity" (Impact factor 7.4). For the last twenty years Dr. Shoenfeld has been the Editor of "Harefuah" – The Israel journal in medicine (Hebrew) and he has edited the Israel Medical Encyclopedia (10 volumes, 5000 items). He had organized over 20 international congresses in autoimmunity.
Dr. Shoenfeld received the EULAR prize in 2005, in Vienna, Austria: "The infectious etiology of anti-phospholipid syndrome". He has received a gold medal from the Slovak Society of Physicians for his contribution to Israel – Slovakia collaboration (March 2006), and is honorary member of the Hungarian Association of Rheumatology. In UC Davis, USA, Dr. Shoenfeld received the Nelsons\s Prize for Humanity and Science for 2008. In 2009 he was honored as Doctoris Honoris Causa, from Debrecen University (Hungary), and from 2009 he is honorary member of the Slovenian National Academy of Sciences. He has recently been awarded a Life Contribution Prize in Internal Medicine in Israel, 2012. Dr. Shoenfeld has educated a long list of students (>25) being heads of departments and institutes.
Autoimmunity, Autoimmune diseases, The Mosaic of Autoimmunity
T-Cell Tolerance and Memory Section LIG, National Institute of Allergy and Infectious Diseases (NIAID)
Polly Matzinger has worked as a bartender, carpenter, jazz musician, playboy bunny, and dog trainer. She is currently chief of the ghost lab and the section on T-Cell Tolerance and Memory. She worried for years that the dominant model of immunity does not explain a wealth of accumulated data and suggested an alternative, the Danger model, which suggests that the immune system is far less concerned with things that are foreign than with those that do damage. This model, whose two major tenets z most of what the immune system seems to do right, as well as most of what it appears to do wrong, covering areas as transplantation,autoimmunity, and the immunobiology of tumors. The model has been the subject of a BBC "horizon" film and was featured in three other films about immunity, as well as countless articles in both the scientific and the lay press. In 2013, her section was assigned to the Laboratory of Immunogenetics.
1986: Köln Film Festival Award for Special Excellence in Educational Films, for Das Immunsystem (German translation of Immunity: the inside story; also translated into French, Japanese, Spanish)
1996: Honorary lifetime member of the Scandinavian Society of Immunology
2002: Listed as one of The 50 Most Important Women in Science by Discover magazine, November 2002
2003: Honorary Doctorate from the Limburg’s Universitaire Centrum, Belgium
2008: Listed in Thompson’s “Highly Cited”
2009: The Fearless Scientist Award yearly scholarship given in honor of Polly Matzinger to a student at the University of Rhode Island
- Danger model of immunity
- Tissue-based class control
- Immune tolerance and activation
Marie Paule Lefranc
CNRS Institute of Human Genetics
University of Montpellier, France
Marie-Paule Lefranc is Professor of Immunogenetics and Immunology, at the University of Montpellier, and Head of the Laboratoire d\ImmunoGénétique Moléculaire (LIGM) at CNRS, Institute of Human Genetics, Montpellier, France, since 1982.
She is also Honorary Senior member of the University Institute of France, Chair of Immunogenetics and Immunoinformatics.She has authored over 300 scientific publications in international journals on the molecular immunogenetics of immunoglobulins, T cell receptors, antibody engineering, and in human genetics and immunoinformatics. Two of her major contributions are, firstly, the finding of large chromosomal deletions including several immunoglobulin genes accounting for the simultaneous
absence of certain isotypes and allowing the overall ordering of the human immunoglobulin constant genes and, secondly, the full characterization of the human T cell receptor gamma locus, for which she received the ROSEN prize of Cancerology in 1988.
She is director of IMGT®, the international ImMunoGeneTics information system®, http://www.imgt.org, that she founded in 1989, at Montpellier. She has defined the IMGT Scientific chart rules and IMGT-ONTOLOGY concepts, which are the foundations of IMGT® which has become the global reference in immunogenetics and immunoinformatics.
Immunogenetics, Immunoinformatics, Antibody engineering, and in Human Genetics