Angiology: Open Access
Open Access
ISSN: 2329-9495
ISSN: 2329-9495
Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010059, P.R. China
Research Article
Correlation between D-dimer and Cancer-associated Thrombosis: A Systematic Review and Meta-analysis
Author(s): Jiayuan Li, Lei Zhang, Yuan Wang, Zhanli Guo, Xiaoting Hu, Ruoning Li, Ying Dong and Jianjun Sun*
This article evaluates the impact of D-dimer on Venous Thromboembolism (VTE) in cancer patients through a systematic review of the literature. The study searched the PubMed, Embase, and Cochrane databases from 2009 to 2023 and conducted a meta-analysis following PRISMA guidelines. The results indicated that D-dimer significantly increased the risk of VTE (HR: 1.29; 95% Confidence Interval (CI): 1.11-1.47, I² = 34.8%). A total of 23,658 patients were included in the analysis of 32 eligible studies, demonstrating moderate heterogeneity among the studies (I²=34.8%). This review not only elucidates the relationship between d-dimer and VTE risk but also underscores the potential clinical utility of this molecular marker. Despite certain methodological limitations, the findings provide a substantial body of scientific evidence to inform future medical decisions and prev.. View More»
DOI:
10.35841/2329-9495.24.12.530