Journal of Clinical Trials
Open Access
ISSN: 2167-0870
+44 1478 350008
ISSN: 2167-0870
+44 1478 350008
Institute for Global Health, University College London, London WC1E 6BT, United Kingdom
Research
Health Outcomes of Children Born/Suspected with Zikv: Protocol for the Zikaction Paediatric Registry in Latin America and the Caribbean
Author(s): Elisa Ruiz-Burga*, Isadora Cristina de Siqueira, Roxanne Melbourne-Chambers, Rosa Maria Bologna, Celia DC Christie, Griselda Berberian, Antoni Soriano-Arandes, Heather Bailey, Paulette Palmer, Andrea Oletto, Breno Lima de Almeida, Maria Lucia Costa Lage, Carlo Giaquinto and Claire Thorne
Background: Although the number of Zika Virus (ZIKV) cases has substantially declined in Latin America and the
Caribbean since the 2015-2016 outbreaks, the cohort of children born at that time and affected by Congenital Zika
Syndrome (CZS) are now around 4-5 years old and experiencing an ongoing impact on their health and development.
Gaps in our understanding remain regarding the outcomes of ZIKV exposure in utero and congenital infection and
the consequences of Congenital Zika Syndrome (CZS) for health throughout childhood.
Methods: The ZIKAction Paediatric Registry is an international multi-centre registry of infants and children with
documented ZIKV exposure in utero (i.e., born to mother with confirmed infection in pregnancy) and/or with
confirmed or suspected congenital ZIKV infection. Clinical teams at participating .. View More»
DOI:
10.35248/2167-0870.21.11.474