Orthopedic & Muscular System: Current Research
Open Access
ISSN: 2161-0533
ISSN: 2161-0533
College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia
Review
A Comprehensive Review Study on Muscular Dystrophy and its Associated Impact on Health and Individuals
Author(s): Basil Alaniz, Turki Alghamdi, Hassan Alhaji, Hussain Alghalaf, Hamza Aldossary, Khaled Aldajani, Rakan Alotaibi and Shamim Shaikh Mohiuddin*
Muscle dystrophy is a genetic muscle disease which leads to progressive loss of muscle mass and a weakened
musculoskeletal system. There are more than 30 types of muscular dystrophy which vary in severity, symptoms, and
causes but the major ones are nine types. Duchenne MD is the most common type of muscular dystrophy, and it
takes place in most of the cases around 50% of them. Usually, boys are more affected by Duchenne MD because of
mutations in X chromosome (X-linked recessive). However, females who carry mutated gene will have few
symptoms. If one of the genes responsible for producing and protecting the protein is impacted, Muscle Dystrophy
can be affected. The family history of muscular dystrophy and young aged boys are at higher risk of developing the
disease (Duchenne MD). However, it exists in all ages, races and both sexes. The general clinical feature of MD is a
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