Angiology: Open Access
Open Access
ISSN: 2329-9495
ISSN: 2329-9495
Department of Cardiology, Sichuan Mianyang 404 Hospital, Yuejin Roa, Mianyang, Sichuan, China
Research Article
Meta-Analysis of Pulmonary Vein Isolation Plus Spatial/Temporal Dispersion Activation Pattern Guiding Catheter Ablation for Non-Paroxysmal Atrial Fibrillation: 10 Years of Studies Update
Author(s): Min Xu*, Qidong Gao, Sitai Liu, Yunfeng Di, Hanlin Wang and Dayong Zhang
Background: Pulmonary Vein Isolation (PVI) is an effective treatment for Paroxysmal Atrial Fibrillation (PAF) but has limited efficacy in Non-Paroxysmal Atrial Fibrillation (NPAF). Spatial/Temporal Dispersion (STD)-guided Catheter Ablation (CA) could offer potential additional benefits. This meta-analysis assessed the advantages and safety of the PVI+STDCA over PVI+Conventional Catheter Ablation (CCA) approaches in NPAF patients, with subgroup analyses highlighting the strategy's potential and challenges. Methods and results: Clinical trials focusing on the PVI+STDCA approach in patients with NPAF were searched in PubMed, MEDLINE, etc. followed by quality checks. Heterogeneity among the pooled data was assessed by the I2 test in a suitable effect model. In this analysis, 17 studies (n=2,203, 82.9% NPAF) were reviewed. The 12-month follow-up revealed that PVI+STDCA significantly in.. View More»