Biochemistry & Pharmacology: Open Access

Biochemistry & Pharmacology: Open Access
Open Access

ISSN: 2167-0501

Gogo Appolus Obediah

Department of Biochemistry, Faculty of Science, Rivers State University, Port Harcourt, Nigeria

  • Research Article   
    Anti-plasmodial Effect of Moringa oleifera Seeds in Plasmodium berghei Infected Albino Rats
    Author(s): Gogo Appolus Obediah* and Nwaokezi Christian Obi

    This study was carried out to investigate the anti-plasmodial effect of Moringa oleifera seeds in Plasmodium berghei infected albino rats to affirm its traditional use in the treatment of malaria in Nigeria and some African countries. The pods of this plant were collected from a garden in Port Harcourt, Nigeria and authenticated by a taxonomist. The seed were dried under shade, deshelled, crushed into powder and extracted with 99% ethanol using rotary evaporator and water bath. Phytochemical investigation was conducted on the powdered seeds using standard method to determine the presence of the bioactive compounds and oral acute toxicity test was also carried out using the modified method of Karber. The in-vivo anti-plasmodial effect of the plant extract of Moringa oleifera (200, 300 and 500 mg/kg), Artemether/Lumefantrine (A/L), Artesunate/Mefloqui.. Read More»
    DOI: 10.35248/2167-0501.20.9.268

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