Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 7868 792050

Francesca Colombo

Medical Department, Cantabria Labs Difa Cooper, Caronno Pertusella (VA), Italy

  • Research Article   
    The Role of an Aloe Vera and Antimicrobial Peptide-Based Skin Cleanser on Microbiome Balance in Acne Vulgaris: A Prospective, Proof of Concept, Open Label Trial
    Author(s): Francesca Colombo and Massimo Milani*

    Introduction: The microbiome represents one of the different factors involved in the pathogenesis of acne. Negative effects on skin microbiome were described after the use of specific acne treatments (like isotreinoin and benzoyl peroxide) or aggressive cleansers. Considering that skin cleansing protocols represent an important step in acne care, the use of a cleanser that preserve or restore the microbiome balance represents a key strategy in the treatment of acne. In this context, a prospective, proof of concept, open label trial was conducted to evaluate the effect of a cleanser containing Aloe Vera and Biopep15 (an oligopeptide with antibacterial and anti-inflammatory activities) on skin microbiome in subjects with acne-prone skin. Materials and methods: Fifteen subjects (11 women and 4 men, mean age 23 ± 3 years),.. View More»
    DOI: 10.35841/2155-9554.23.14.632

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