Angiology: Open Access
Open Access

Dr, Department of Medicine, University of Missouri, USA

Publications

• Research Article   
  Linking Cancer to Metabolic Syndrome through it’s Individual Contributory Components: Oxidative Stress and Renin-Angiotensin-Aldosterone Axis Dysregulation
  Author(s): Chirag H Mandavia*
  
  Impaired signaling pathways as a result of the increased oxidative stress and general metabolic dysregulation seen in metabolic syndrome may contribute to the increased cancer risk seen in otherwise healthy patients; and subsequent development of progressive cancer characterized by metastatic process. Oxidative stress leading to insulin resistance is a major component of the metabolic syndrome. Dysregulation of the Renin-Angiotensin-Aldosterone (RAAS) axis is known to be one of the major risk factors for metabolic syndrome; and recently has been shown to play a significant contributory role in the development of oxidative stress; leading up to insulin resistance; in the metabolic syndrome by several different groups. In recent years; angiotensin and aldosterone have emerged as important contributory pathogenic factors for the development of metabolic syndrome; primarily through their .. View More»
  DOI: 10.35248/2329-9495.19.7.225

  Abstract HTML PDF