Journal of Clinical Chemistry and Laboratory Medicine
Open Access
ISSN: 2736-6588
ISSN: 2736-6588
Department of Molecular Medicine, School of Medical Sciences, College of Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Research Article
Procalcitonin as a Surrogate Marker of Sepsis in People Living with HIV/AIDS: A Case Study at Komfo Anokye Teaching Hospital, Ghana
Author(s): Charity Frimpong*, Francis Agyemang-Yeboah, Christian Obirikorang, Yasmine Hardy, Kwaku Nyame, Isaac Acheampong, Opoku Kwame, Sampson Donkor, Bright Oppong Afranie and Beatrice Amoah
Sepsis is one of the commonest problems associated with the admission of critically ill patients, especially HIV/AIDS
patients at the Critical Care Units of Hospitals. Diagnosis and prognosis of sepsis in the clinical setting is a challenge
since there is no diagnostic tool for measuring the severity and course of sepsis. Therefore, this study was designed to
assess the use of Procalcitonin as a surrogate marker of sepsis in a case-control study of both septic and non-septic
HIV/AIDS and also for the determination of its cut-off threshold for sepsis.
Using a hospital-based case–control study design, 100 HIV/AIDS patients comprising of 66 septic cases and 34 nonseptic
were recruited from the Emergency Department of Komfo Anokye Teaching Hospital (KATH), Ghana. Sepsis
was defined using the Systemic inflammatory response syndrome (SIRS) criteria. Serum Proc.. View More»