Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Monastir, Avenue Avicenne, Monastir 5019, Tunisia
Research Article
Application of Simplex-Centroid Design Methodologies to Optimize the Anti-bacterial and Anti-candidal Activity of the Mixture of Mentha pulegium, Pituranthos chloranthus and Thymus algeriensis Essential Oils
Author(s): Zoubeyda Souiy*, Ameur Elaissi, Ibrahime Jlassi, Wala Sghair, Noureddine Allouch, Maha Mastouri and Boubaker Krifia
This work aims to study the antimicrobial activities of the essential oils of M. pulegium, P. chloranthus and T. algeriensis and to identify the antagonistic or synergistic impacts of their combinations. Antimicrobial activities were analyzed by disc diffusion and microdilution against six foodborne microbial strains (Staphylococcus aureus, Bacillus cereus, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa and Candida albicans). That's why, to predicate the optimal mix, we are using the Augmented Simplex Centroid Design. The chemical composition shows that the main compound of M. pulegium were pulegone (50.31%) and menthone (26.92%). For P. chloranthus EO, The major constituents were dillapiole (13.56%) and pregnane (8.47%) and the main products of T. algeriensis EO are Camphor (14.0.. View More»
DOI:
10.35248/2167-0412.21.10.365