Clinical Pediatrics: Open Access
Open Access
ISSN: 2572-0775
+44 1223 790975
ISSN: 2572-0775
+44 1223 790975
Lutheran Children's Hospital, USA
Research Article
Comparison of Homozygous for Delta F508 Mutation Nutritional Status, Lung Function Outcomes, Bacterial Growth, Antibiotic Treatments and Therapeutic Outcomes between the Amish and Non-Amish in a Single Pediatric Cystic Fibrosis Centre: A Retrospective Case-Controlled Study
Author(s): Rajeswary Padman Padmalingam, Denise Gilham, Tina Laturner, Ron Jones, Gordon Bokhart, Alyaa Hussien*, Chelsea Hamilton, AbeerOmar and Rachel McCafferty
There exists evident differences in the health and the care received of the Amish people in comparison to the general population. Amish patients were 100% homozygous for delta F508 mutation versus 12% in the non-Amish population (P=0.057). The Amish community was prescribed dietary supplements at a rate of 89% versus 50% for non-Amish (P=0.087). BMI > 75th percentile was 51.25% in Amish patients and 61.25% in non-Amish patients (P=0.31). Mean FEV1 value was 83.6% versus 100% while mean FEF 25-75 value was 58% versus 86% for Amish and nonAmish people respectively. There was substantial variance in the number of episodes of the same infection per patient between Amish and non-Amish population (1 IQR 0–1 versus 0 IQR 0–1; p=0.012). The rate of antibiotic prescribing per patient in the Amish group was 7.9 perceptions versus 2.2 prescriptions. The study aims to create the be.. View More»
DOI:
10.35248/2572-0775.19.4.151