Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

Alexandra Price

Dr. Phillip Frost Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA

  • Case Report   
    A Challenging Case of Atypical Adult Onset Still's Disease Clinically Mimicking Dermatomyositis with Distinctive Histopathologic Findings
    Author(s): Andjela Egger*, Miranda Rosenberg, Alexandra Price and Jeong Hee Cho-Vega

    A 23-year-old woman from Bangladesh presented with a 6-week history of spiking fevers, myalgias, arthralgias, pruritic rash, marked granulocytosis and lymphadenopathy. On presentation to the emergency department she had brown lichenified plaques on the upper chest and neck; her back had flagellate-like erythema. Hand exam revealed hyperpigmented papules over the metacarpophalangeal joints without periungual capillary loop dilatation. Labs were notable for: minimally positive ANA (1:40), mild transaminitis (AST 56, ALT 73), as well as elevated aldolase (13.8), LDH (1,368), sedimentation rate (>140), C reactive protein (7.5) and ferritin (10,248). She also had a negative Anti Jo1 antibody, rheumatoid factor, and CK (<20). An extensive infectious workup was negative. CT of the chest/ abdomen showed generalized lymphadenopathy with mild splenomegaly. Punch biopsies from the hands an.. View More»

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