Journal of Clinical Trials

Journal of Clinical Trials
Open Access

ISSN: 2167-0870

+44 7868 792050

Alexander G. Chuchalin

Russian National Research Medical University, Ostrovityanova 1., 117997 Moscow, Russian Federation

  • Research Article   
    Computational Systematics of Nutritional Support of Vaccination against Viral and Bacterial Pathogens as Prolegomena to Vaccinations against COVID-19
    Author(s): Ivan Y. Torshin*, Olga A. Gromova and Alexander G. Chuchalin

    A total of 6,628 PUBMED-registered publications on the relationships between the effects of vaccination and the provision of micronutrients have been studied by methods of topological analysis of text data. In case of insufficient intake of certain micronutrients, the functioning of the acquired immunity is disrupted resulting in an imbalance of populations of T-cells CD4+/CD8+ and of B-lymphocytes. Nutritional supplements of folate, vitamins A, D and B12, which are recognized regulators of cell division, support a wide range of lymphocyte populations. Trace elements zinc, iron, selenium, manganese and omega-3 polyunsaturated fatty acids are also important for supporting the mechanisms of acquired immunity. The data presented show that a course intake of these micronutrients by patients planning vaccination can significantly improve its effectiveness. In particula.. View More»
    DOI: 10.35248/2167-0870.21.11.478

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