Journal of Clinical Trials
Open Access

Department of Gastroenterology, Cukurova University, Adana, Turkey

Publications

• Research Article   
  Erythrocyte Sedimentation Rate and C-Reactive Protein are Markers for Tumor Aggressiveness and Survival in Patients with Hepatocellular Carcinoma
  Author(s): Brian Carr*, Akkiz H, Guerra V, Donghia R, Yalçin K, Karaogullarından U, Altıntas E, Ozakyol A, Şimşek H, Balaban HY, Balkan A, Uyanıkoglu A and Ekin N
  
  Introduction: Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are acute phase reactants in clinical use for monitoring inflammatory diseases for several decades. CRP is also prognostically useful in several cancers. Objective: To evaluate the role of ESR as a possible indicator of tumor biology and survival in patients with hepatocellular carcinoma (HCC). Methods: A large cohort of HCC patients in Turkey was examined retrospectively for clinical and tumor characteristics with respect to blood CRP and ESR levels. Results: Portal vein thrombosis and high Aggressiveness Index were significantly related to elevated CRP or ESR levels and especially to the combination of elevated CRP and ESR, both in the total cohort and in patients with small tumors &l.. View More»
  

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