Immunome Research
Open Access
ISSN: 1745-7580
ISSN: 1745-7580
Zotarelli Filho IJ
Brazil
Review Article
Major Considerations and Outcomes of Clinical Studies on Vitamin D Deficiency in Patients with Crohn’s Disease: Systematic Review
Author(s): Gouvêa Faria MA, Germany Faria DC, de Quadros LG, Kaiser Júnior RL, Liedtke Kaiser FS, Crivelin L, Zotarelli Filho IJ, de Santana MF and Casella TGouvêa Faria MA, Germany Faria DC, de Quadros LG, Kaiser Júnior RL, Liedtke Kaiser FS, Crivelin L, Zotarelli Filho IJ, de Santana MF and Casella T
Introduction: The literature shows a bimodal incidence of Crohn's disease in relation to age, with peaks from 15-40 and from 50-80 years and more women have Crohn's disease than men. Clinical studies have shown a direct correlation of vitamin D deficiency with Crohn's disease.
Objective: Using a systematic review, the objective of this study was to identify the main correlations and outcomes of clinical studies about vitamin D in Crohn's disease.
Methods: Following the rules for systematic reviews (PRISMA), the key search terms used were Crohn’s disease, vitamin D, clinical studies, immunotherapy and quality of life. After applying exclusion criteria, 117 articles were included and discussed in this study.
Conclusion: The prevalence of low serum vitamin D levels has .. Read More»
DOI:
10.4172/1745-7580.1000163
