Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+1 504 6082390

Zhenxiang Wang

Publications
  • Research Article
    Cancer Specific CTL Expansion with ZYX Bioreactor
    Author(s): Yongxin Zhang, Ying Wang, Zhenxiang Wang, Monica Zhang and Zhenying WangYongxin Zhang, Ying Wang, Zhenxiang Wang, Monica Zhang and Zhenying Wang

    Objective: The use of therapeutic immune cell subsets is becoming an increasingly cost-effective and attractive strategy for the treatment of cancer. Nonetheless, the field of cell therapy is hampered by the inability to consistently generate and expand sufficient numbers of high quality cells from a majority of patients. To address this critical issue, the investigators developed a sophisticated bioreactor technology that maximizes metabolic support and minimizes the damaging shear-stress forces, automatically monitors functional correlates to allow cell harvest at peak functional capacity, and permits cell sorting in situ to minimize cell loss and microbial contamination. In current study, the established cancer-specific CTL expansion system will be tested for its potency of cancer cell killing both in vitro and in vivo. Methods: To te.. Read More»
    DOI: 10.4172/2155-9899.1000398

    Abstract PDF

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