ISSN: 2165-7548
+44 1223 790975
Yosuke Homma
Japan
Research Article
The Discrepancy of the Minimum Inhibitory Concentration Results for Methicillin-Resistant Staphylococcus aureus by Various Measurement Methods
Author(s): Yuka Kitano, Shigeki Fujitani, Haruaki Wakatake, Machi Yanai, Sari Umekawa, Yosuke Homma and Yasuhiko Taira
Yuka Kitano, Shigeki Fujitani, Haruaki Wakatake, Machi Yanai, Sari Umekawa, Yosuke Homma and Yasuhiko Taira
Background: It has been postulated that there exists a discrepancy of methicillin-resistant Staphylococcus aureus (MRSA) minimum inhibitory concentration (MIC) results from various measurement methods. The association between higher MRSA MIC (MIC ≥ 2 μg/ml) and worse clinical outcome has been previously reported. Therefore, it is clinically essential to investigate whether such a discrepancy exists between the different MIC measurement methods.
Methods: From November 2009 to March 2011, 55 MRSA isolates were prospectively obtained at two emergency departments in Japan. The MIC of the isolates were measured by Etest® and five broth microdilution (BMD) methods, namely Eiken®, MicroScan® prompt method, MicroScan® turbidity method, Phoenix® and Vitek2® system, respectively. The MIC resu.. View More»
DOI:
10.4172/2165-7548.1000286