Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Ying Liu
Beijing Obstetrics and Gynecology Hospital,
Beijing 100026
China
Review Article
The Influence of Pregnancy on the Prognosis of Endometrial Atypical Hyperplasia and Adenocarcinoma with Assisted Reproductive Technology after Fertility-Sparing Therapy: A Systematic Review and Meta-Analysis
Author(s): Lu-ping Yu, Shi-yi Zhao, He Chao and Ying LiuLu-ping Yu, Shi-yi Zhao, He Chao and Ying Liu
Objective: To evaluate live birth rates and the influence of pregnancy on the prognoses of young women (<40 years old) with early-stage endometrial cancer (EC) and atypical complex hyperplasia (AH) who were treated by conservative management followed by assisted reproductive technology (ART).
Methods: A meta-analysis of observational studies with a random-or fixed-effects model as appropriate.
Results: A study of 527 women from 23 studies included 201 women to assess how prognosis might be influenced by pregnancy. Analysis of no pregnancy studies as the reference group pointed to a statistically significant positive association between pregnancy and decreased risk for recurrence (RR) of 0.56, 95% confidence interval (CI): 0.37-0.84. Eighteen studies including 104 women enabled determination of live birth rates o.. View More»
DOI:
10.4172/2375-4508.1000153