Department of Anesthesia, Capital Institute of Paediatrics, Beijing, PR. China
Dr Luo's research focuses on urinary bladder inflammation and cancer, specifically the interplay between the bladder and the immune system. This field is challenging due to a lack of proper animal models. In the early of the 2000s, Dr. Luo's team used genetic engineering technology to develop a novel transgenic murine model that expresses the membrane form of the well-defined model antigen ovalbumin (OVA) as a self-antigen on the urothelium. This model can develop autoimmune-based bladder inflammation upon introduction of OVA-specific T and/or B cells.