Emergency Medicine: Open Access
Open Access
ISSN: 2165-7548
+44 1223 790975
ISSN: 2165-7548
+44 1223 790975
Yasuhiko Taira
Kanagawa Prefecture,
Kawasaki City, 2-16-1 Sugao Miyamae-ku, 216-8511
Japan
Research Article
The Discrepancy of the Minimum Inhibitory Concentration Results for Methicillin-Resistant Staphylococcus aureus by Various Measurement Methods
Author(s): Yuka Kitano, Shigeki Fujitani, Haruaki Wakatake, Machi Yanai, Sari Umekawa, Yosuke Homma and Yasuhiko TairaYuka Kitano, Shigeki Fujitani, Haruaki Wakatake, Machi Yanai, Sari Umekawa, Yosuke Homma and Yasuhiko Taira
Background: It has been postulated that there exists a discrepancy of methicillin-resistant Staphylococcus aureus (MRSA) minimum inhibitory concentration (MIC) results from various measurement methods. The association between higher MRSA MIC (MIC ≥ 2 μg/ml) and worse clinical outcome has been previously reported. Therefore, it is clinically essential to investigate whether such a discrepancy exists between the different MIC measurement methods.
Methods: From November 2009 to March 2011, 55 MRSA isolates were prospectively obtained at two emergency departments in Japan. The MIC of the isolates were measured by Etest® and five broth microdilution (BMD) methods, namely Eiken®, MicroScan® prompt method, MicroScan® turbidity method, Phoenix® and Vitek2® system, respectively. The MIC resu.. View More»
DOI:
10.4172/2165-7548.1000286