Cloning & Transgenesis
Open Access

Xiaojing Kang

Publications

• Research Article
  Association of HLA-DRB1*1201/02, DRB1*0701/02, DQA1*0302 and DQB1*0303 Alleles with population Uygur patients of vitiligo
  Author(s): Xiaojing Kang*, Junqin Liang, Li Chai, Lvjiao Peng, Shirong Yu, Xiujuan Wu and Juan Zhao Xiaojing Kang*, Junqin Liang, Li Chai, Lvjiao Peng, Shirong Yu, Xiujuan Wu and Juan Zhao
  
  Vitiligo is associated with different human leukocyte antigens (HLAs), but the relationship of HLAs and Uygur population people is unknown. The study aimed to investigate whether there is an association between HLADRB1* 1201/02, DRB1*0701/02, DQA1*0302, and DQB1*0303 and the incidence of vitiligo in a Chinese Uygur population and further evaluate their effect on the clinical features of vitiligo. A total of 308 Chinese Uygur patients with vitiligo and 310 healthy controls were included in the study. HLA-DRB1*1201/02, DRB1*0701/02, DQA1*0302 and DQB1*0303 allele distribution was investigated by polymerase chain reaction (PCR), the sequence-specific primer method. Family history, clinical types, phase, etc. were evaluated. The data were analyzed by the chi-square test. A significant difference was found in the distribution of HLA-DRB1*1201/02, DRB1*0701/02, DQA1*0302, and DQB1*0303 betw.. View More»
  DOI: 10.4172/2168-9849.1000157

  Abstract PDF

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