Andrology-Open Access
Open Access
ISSN: 2167-0250
+44 1300 500008
ISSN: 2167-0250
+44 1300 500008
Xiansheng Zhang
Urology, The First Affiliated Hospital,
Hefei, Anhui
China
Research Article
Combination of Sertraline and Sildenafil versus Sertraline Monotherapy in the Treatment of Acquired Premature Ejaculation without Concomitant Diseases
Author(s): Xiansheng Zhang, Dongdong Tang, Jiajia Yang, Kai Shi, Jingjing Gao, Zongyao Hao, Jun Zhou and Chaozhao LiangXiansheng Zhang, Dongdong Tang, Jiajia Yang, Kai Shi, Jingjing Gao, Zongyao Hao, Jun Zhou and Chaozhao Liang
Objective: To determine the efficacy and safety of sertraline monotherapy and combination therapy with sertraline and sildenafil in the treatment of APE without concomitant diseases.
Methods: The study was conducted in 120 outpatients diagnosed with APE but without concomitant diseases. These patients were randomly divided into two groups: group A was treated with 50 mg sertraline daily; group B was treated with 50 mg sertraline daily and 50 mg sildenafil as needed. Assessment of the efficacy and safety of the two therapies was performed after 4 and 8 weeks. Patient or partner reports of Intravaginal Ejaculatory Latency Time (IELT), Premature Ejaculation Profile (PEP), Clinical Global Impression of Change (CGIC), and Treatment-Emergent Adverse Events (TEAEs) were assessed in this study. All the assessments were compared in the two groups after the treatment period. The effic.. View More»
DOI:
10.4172/2167-0250.1000117