ISSN: 2155-9937
						Wei Li 
	
					    												Department of Radiology/CAI, Walgreen Building, Suite G507, Evanston Hospital, 
2650 Ridge Ave, Evanston, IL 60201
Tanzania						                            
                            
						
 Research Article
												Would Sub-regional Analysis Improve Sensitivity in Knee dGEMRIC? 						
Author(s): Wei Li, Hongyan Du, Pottumarthi V. Prasad
Wei Li, Hongyan Du, Pottumarthi V. Prasad
             
						
												
				 Purpose: To evaluate if sub-regional analysis could offer higher sensitivity than full-thickness analysis when quantifying dGEMRIC data of the knee.
Materials and methods: A dGEMRIC data set of medial femoral cartilage of the knee, including thirteen patients with osteoarthritis (diseased) and fourteen asymptomatic subjects (control), was reanalyzed with sub-regional analysis, i.e. using two ROIs (regions of interest) representing superficial region and deep region of the cartilage respectively, in addition to full-thickness ROI. Comparisons were made in T1pre (spin-lattice relaxation time without contrast administration), T1Gd (after Gd-DTPA2- administration), and ΔR1 (the change of relaxation rate) obtained with the three analysis methods.
Results: Differences between superficial region and deep region in T.. View More»
				  
												DOI:
												 10.4172/2155-9937.1000105