Andrology-Open Access
Open Access
ISSN: 2167-0250
ISSN: 2167-0250
Walker K
Tanzania
Research Article
The Effect of Processed Total Motile Sperm Counts and Twenty Four Hour Sperm Survival on the Efficacy of Intrauterine Insemination in Male Infertility
Author(s): Branigan E, Estes A and Walker KBranigan E, Estes A and Walker K
Objective: To compare the effectiveness of IUI, based on Pre-treatment Semen analysis results, in treating male factor infertility.Design: A retrospective cohort design of 1,768 infertile couples undergoing 5,219 IUI cycles, who had pretreatment advanced semen analysis were evaluated. An advanced semen analysis consists of a basic semen analysis and processed total motile sperm counts through a density gradient sperm prep and recording 24 hours sperm survival of these sperm culture media in an incubator. Logistic regression analysis was used to assess the significance of prognostic factors in sperm parameters to predict the pregnancy rates with IUI.Results: No basic semen analysis parameter accurately predicted IUI success. Clinical pregnancy rate for first cycle of IUI was 15.6% when >10 × 106 processed.. View More»
DOI:
10.4172/2167-0250.1000191