Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Thiago Celestino Chulam
Surgeon Member of Head and Neck Surgery and Otorhinolaringology Department of A C Camargo Hospital,
Professor Antonio Prudente Street, 211 Sao Paulo, Brazil-01509-900
Brazil
Research Article
Prognostic Factors in Patients with Well-Differentiated Thyroid Carcinoma with Locoregional Recurrence Submitted for Salvage Treatment
Author(s): Bernardo Fontel Pompeo, Thiago Celestino Chulam, Ana Lucia Noronha Francisco and Luiz Paulo KowalskiBernardo Fontel Pompeo, Thiago Celestino Chulam, Ana Lucia Noronha Francisco and Luiz Paulo Kowalski
Background: Well-differentiated thyroid carcinoma is characterized by an excellent prognosis; however, recurrence rates range from 5% to 23%, and mortality after salvage treatment ranges from 38% to 69%.
Objectives: To identify prognostic factors in patients who have undergone salvage therapy for well-differentiated thyroid carcinoma.
Patients and methods: This is a retrospective cohort series including 102 patients with respectable locoregional recurrences who underwent salvage treatment. One hundred twenty loco-regional recurrences were observed amongst 102 patients. Univariate survival analysis was performed using the Kaplan-Meier method.
Results: Five-year overall survival rates were significantly associated with age over 45 years (67.6%) (p <0.0001), site of recurrence (local or r.. View More»
DOI:
10.4172/2167-7948.1000146