Journal of Applied Pharmacy
Open Access
ISSN: 1920-4159
+44 1300 500008
ISSN: 1920-4159
+44 1300 500008
Sundus Riaz
Pakistan
Review Article
Bacterial and Liposomal Vector Guided Drug Delivery System via Tumor
Markers Carrier Gene to Treat Neoplasm
Author(s): Beenish Naeem Awan, Nosheen Fatima, Sundus Riaz, Sadia Malik and Wajiha AhmadBeenish Naeem Awan, Nosheen Fatima, Sundus Riaz, Sadia Malik and Wajiha Ahmad
The main goal of cancer therapy is to not only treat cancer but also to protect healthy cells from the toxic effect of the chemotherapeutic agent. For this purpose, different modern techniques are devised. The significant localized chemotherapeutic effect can be induced by combining all these techniques. Bacteria have been used as a novel organism for chemotherapy. Many new chemotherapeutic drug delivery techniques have come into existence these techniques involve bacterial cloning. The cloned bacteria contain either drug carrying gene or a prodrug-activating enzyme. Bacteria chosen for therapy should be able to grow in hypoxic tumor condition. Experiments done on Clostridium (anaerobic bacterium), produces tumor suppression in many animals.
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DOI:
10.4172/1920-4159.1000206