Journal of Physical Chemistry & Biophysics

Journal of Physical Chemistry & Biophysics
Open Access

ISSN: 2161-0398

+44 1478 350008

Soo Mi Kim

Soo Mi Kim
Chonbuk National University Medical School,
Republic of Korea

  • Research Article
    Biological Activities of Resveratrol against Cancer
    Author(s): Soo Mi Kim and Sung Zoo KimSoo Mi Kim and Sung Zoo Kim

    Resveratrol (RSV) is a polyphenolic compound naturally found in grapes, peanuts, and berries. Considerable research has been performed to determine the benefits of RSV against various human diseases, especially cancer. Despite numerous studies on the effect of RSV on cancer, correct understanding of its mechanism is still far from certainty. This review summarizes the recent results on the molecular mechanisms and pathways of actions of RSV against major cancers. According to investigations accomplished worldwide, RSV targets pathways such as cell cycle progression, autophagy, apoptosis, angiogenesis and invasion/metastasis to attenuate cancer progression mediated through PI3K/Akt/mTOR, Wnt, ROS, NF-κB, BAX/Bcl-2, AMPK, ERK, MAPK signaling pathway. Considering the sideeffects and data of clinical trials, RSV can be used for its maximum benefits in human diseases. Available publi.. View More»
    DOI: 10.4172/2161-0398.1000267

    Abstract PDF

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