Medical & Surgical Urology
Open Access
ISSN: 2168-9857
+44-20-4587-4809
ISSN: 2168-9857
+44-20-4587-4809
Sivasubramaniyan V
Sri Sathya Sai Institute of Higher Learning,
Vidyagiri, Prasanthinilayam, Andhra Pradesh
India
Research Article
Non-invasive Quantitative Characterization of Skeletal Metastasis in Carcinoma Prostate by Tc99m MDP Bone Scans Using Dr. V. Sivas Retention Ratio in Correlation with Serum PSA Levels
Author(s): Sivasubramaniyan V and Venkataramaniah KSivasubramaniyan V and Venkataramaniah K
Background: In patients suffering from carcinoma prostate the incidence of skeletal metastases had been found to be very high. The presence of skeletal metastasis could be inferred by the multiple focal hotspots in the skeletal tissue. The metastatic nature of the hotspots could be inferred by multiple lesions, asymmetric distribution with increased tracer concentration. In the case of Solitary focal spot in the bone scan metastatic nature could not be attributed to it. The invasive biopsy procedure could only confirm or discard the metastatic involvement. A new non-invasive Scintimetric characterization and evaluation of skeletal hot spots in bone scans of carcinoma prostate patients was proposed and tested. Materials and methods: The bone scan was done 4 and 24 hours after intravenous injection of 15 to 25 mCi of Tc99m Methylene Di-Phosponate with adequate hydration using the e-cam .. View More»
DOI:
10.4172/2168-9857.1000164