Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
+44 1478 350008
ISSN: 2161-0401
+44 1478 350008
Sirajudheen P
Department of chemistry, WMO Imam Gazzali Arts and science College, koolivayal, Cherukattoor Post,
Wayanad, Kerala
India
Research Article
Synthesis Characterization and Antimicrobial Activity of N-nitroso-2, 6-Diphenylpiperidin-4-One Semicarbazone
Author(s): Mubarak S, Sirajudheen P, Shebin KSM, Muhasina M and Rishana TMubarak S, Sirajudheen P, Shebin KSM, Muhasina M and Rishana T
Among the family of heterocyclic compounds, The nitrogen containing six membered heterocyle, the piperidine structural was the most dominant and very prevalent element in nature and often found to be naturally occurring bioactive compounds such as alkaloids. Piperidin-3-one derivatives are used as precursors for the synthesis of antimalarial agents febrifugine and Isofebrifugine. Piperidin-4-ones mostly display varied and potent biological properties such as antiviral, antitumour, analgesic, antimicrobial, fungicidal, herbicidal, insecticidal, antihistaminic, anti-inflammatory and anticancer. CNS stimulant and recent reports suggest that compounds containing piperidin-4-one moiety elicit excellent activity when aromatic substitutions are present at 2- and/or 6-positions. In this work, the compound N-nitroso-2,6- diphenylpiperidin-4-one semicarbazone has been prepared and analyzed. The.. View More»
DOI:
10.4172/2161-0401.1000141